While the second declension is considered to be masculine/neuter are there not in fact many feminine nouns?
Names of countries and towns in -us (-os) are Feminine: as, Aegyptus , Corinthus . Also many names of plants and gems, with the following: alvus, belly; carbasus, linen (pl. carbasa, sails, N.); colus, distaff; humus, ground: vannus, winnowing-shovel.
Many Greek nouns retain their original gender: as, arctus (F.), the Polar Bear; methodus (F.), method.
I’ll just add that “many” is not the word to use. You could read a lot of Latin and never or rarely see one.