Quis - Renaissance

Cajetan scripsit: “Quoad secundum, et redditur ratio quare apponatur supra relationem realitas; et quis sit respectus realis, et quis rationis.”

“As to the second, and the reason why it is beyond real relation is given; both what a real relation is, and what [a relation] of reason [is].”

What does “quis” (2 times) mean here? It seems to mean “what” but quis as far as i am aware usually means who (m/f). Can Quis mean “what”?

Yes quis can mean what when it refers to a masculine noun.

realitas is the subject of apponatur.

Thanks for the confirmation and the correction.